Annexin V and apoptosis – A review

Abstract

Apoptosis is an important mechanism happening in our body that basically is a form of programmed cell death developed to remove unwanted, damaged or senescent cells from tissues. Analysing the number of cells undergoing cell death helps us understand the underlying mechanisms of pathobiology. Annexin V has an affinity to apoptotic cells by binding to cell membrane proteins. Annexin V assays have been developed to further analyse the degree of apoptosis occurring during health and disease.