Diabetes and periodontitis - a bidirectional relationship – A review of current literature

Abstract

Periodontal disease and diabetes mellitus are two most common diseases affecting millions of people globally. They share common pathobiologic mechanisms involving inflammatory pathways that further affect the  severity and progression of the disease. An ensuing bidirectional relationship has been proven by various studies, signifying the importance of prompt treatment strategies to control the effect of both conditions on each other. This review highlights the current literature available and provides insights regarding the underlying mechanisms of pathogenesis.