Association between Haematological Parameters and Recurrent Apthous Stomatitis
Original Research
DOI:
https://doi.org/10.56501/intjcraniomaxillofacsurgrehab.2022.686Keywords:
Recurrent apthous stomatitis, Vitamin B12, Folic acid, Heamoglobin, Apthous ulcerAbstract
Objectives:
Recurrent apthous stomatitis (RAS) one of the most common diseases affecting the oral mucosa. The etiology is multifactorial. The aim of this study was to establish the relationship between recurrent apthous stomatitis and Vitamin B12, folic acid and Hemoglobin levels in patients with recurrent apthous stomatitis.
Materials and Methods:
This observational study was conducted for a period of two years. Patients with systemic conditions exhibiting oral ulcers were excluded. Serum levels of Vitamin B12, FA and Hb was evaluated.
Results:
Fifty two percent of the patients were females. The mean age of the patients was 35.3+10.28. Based on the size, 90% of the ulcers were of the minor type. RAS was seen in 56% of patients with low normal and 21% patients with deficient Vitamin B12 level compared to five patients with normal Vitamin B12 level. RAS was observed in 47% patients with normal and low normal level of FA and 4% patients with deficient FA level. Two female patients and one male patient were anemic compared to ten female patients and ten male patients with normal Hb levels. The mean Vitamin B12, FA and Hb levels among the patients with RAS were 387.74 +264.88, 7.02+4.95ng/ml, 13.23+ 2.15 g/dl respectively.
Conclusion:
The results show that Hematinic deficiencies are observed in patients RAS. Hence, hematinic deficiencies should be considered in diagnosis and management of RAS.
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Copyright (c) 2022 Gidean Arularasan, Jagdish Ebinezar, Daniel Sathyasundaram
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