Recurrent metastatic malignant granular cell tumor of the back presenting with axillary mass: A rare case report and review of the literature

Abstract

Malignant granular cell tumor (MGCT) is a rare aggressive tumor that comprises 0.5%–2% of all granular
cell tumors. They most commonly occur on lower extremity, nuchal region, chest wall, gastrointestinal
tract, and head and neck. We report fine needle aspiration and histopathological findings of a rare
case of recurrent MGCT presenting with axillary mass along with a tumor on the right back in a
56-year-old female. Tumor cells with abundant granular eosinophilic cytoplasm showing pleomorphism,
enlarged vesicular nuclei, prominent nucleoli, 4–5 mitotic figures/10 high-power field, periodic acid–
Schiff-positive diastase-resistant cytoplasmic granules, and metastasis in the axillary lymph node were
also suggestive of MGCT. Immunohistochemically, the tumor cells were positive for S-100 confirming
the diagnosis