Trichoblastoma – A rare case of benign skin lesion

Authors

  • Diwagar N Assistant Professor, Department of Pathology , Saveetha Medical College and Hospital, Saveetha Nagar, Thandalam, Chennai 602105, Tamil Nadu , India
  • Chander SK Chander SK , Postgraduate,Department of Pathology , Saveetha Medical College and Hospital, Saveetha Nagar, Thandalam, Chennai 602105, Tamil Nadu , India
  • Sulochana S Professor, , Department of Pathology , Saveetha Medical College and Hospital, Saveetha Nagar, Thandalam, Chennai 602105, Tamil Nadu , India
  • Chitra S Professor, Department of Pathology , Saveetha Medical College and Hospital, Saveetha Nagar, Thandalam, Chennai 602105, Tamil Nadu , India

DOI:

https://doi.org/10.56501/intjclinicopatholcorrel.v6i2.671

Keywords:

Trichoblastoma, benign hair follicle tumor, germinative cell tumor

Abstract

Trichoblastoma is a rare type of benign hair follicle tumor arising from follicular germinative cells, presenting as a solitary mass of brown/black nodule usually on head , neck and other extremities of body. It can arise at any age and sex, however, it is more common among adults between the ages of 40 and 50 years. It is a dermal, epithelial and stromal neoplasm consisting of proliferation of basaloid cells in a stroma resembling perfollicular fibrous tissue. Although benign, surgical biopsy is necessary to analyze under histopathological examination for diagnosing and differentiating trichoblastoma from basal cell carcinoma or harbor malignant characteristics. It typically has a favorable prognosis, with a very low incidence of recurrence, progression or association with malignancy. Here we present a case of a 67 year old female who presented with a nodular swelling  on the right side of nose for past 3 months. The swelling was painless. On examination the nodular swelling was 2 x 2 x 1cm and firm in consistency. An excision biopsy was done. Histopathological  examination showed features of trichoblastoma. This case is reported here due to its extreme rarity.

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References

Ackerman AB, Reddy VB, Soyer HP. Neoplasms with follicular differentiation. 2nd ed. New York: Ardor Scribendi; 2001. p. 1109.

Ghigliotti G., De Col E., Parodi A. et al. Trichoblastoma: is a clinical or dermoscopicdiagnosis possible? J EurAcad DermatolVenereol 2016; p 1978-198.

Karmarkar PJ, Mahore SD, Wilkinson AR. Solitary trichoblastoma. Indian J Pathol Microbiol 2009; p. 277-278.

Headington J.T.: Tumours of hair follicle –A review –Am. Jour. Of Pathol. 1976 ;85 : 479 –514.

Laxmi Rao, Vidya Monappa, Mohammed Musheb: Cutaneous nodule on face: Admantinoid Trichoblastoma –A unique tumour –Our Dermatol. Online 2013; 4(2) : 218 –220.

Yamamoto O, Asahi M: Cytokeratin expression in trichoblastic fibroma(small nodular type trichoblsroma), trichoepithelioma and basal cell carcinoma-BJD 1999;140;8-16.

Misago N, Narisawa Y:. Tricholemmal carcinoma in continuity with trichoblastoma within nexus sebaceous. Am J Dermatopatho1 20 02324 :149-155.

Luciana Takata Ponters, Andre Luiz Siiao, Fernando dos Ramos Seuling et. al. : Mohs Micrographic Surgery on recurrent trichoblastoma -Surg. Cosmet Dermatol 2012 ;4(1) : 93 –6.

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Published

2022-10-10

How to Cite

N, D. ., SK , C., S, S. ., & S, C. . (2022). Trichoblastoma – A rare case of benign skin lesion. International Journal of Clinicopathological Correlation, 6(2), 1–3. https://doi.org/10.56501/intjclinicopatholcorrel.v6i2.671

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Section

Case Report