Medical students and professionals attitudes towards, awareness of, and interest in Animal research: Original Research

Cader S A

doi:10.56501/intjclinicopatholcorrel.v7i1.855

Authors

Cader S A Periodontist and Implantologist, Dr. Shaik's Dental Clinic and Implant Center, Broadway, Chennai

DOI:

https://doi.org/10.56501/intjclinicopatholcorrel.v7i1.855

Keywords:

Animal research, clinical trials, medical apprentices, perception

Abstract

Introduction

Animal experimentation in drug trials, basic medical learning, the efficacy of drugs, their mechanism of action, behavioural and numerous neurobiological studies are ongoing before future usage in human trials. This current paper aims to investigate the attitudes, awareness and interest of animal research study among students and practitioners.

Materials & methods

A self-structured survey quiessionaires designed on animal research interest, perceptions, research update, ethical aspects, need for study, and justifications on clinical trials. This cross sectional survey study was conducted among medical practitioners and students in a short period of May 2021. The data were analysed by descriptive statistics using IBM SPSSv23.

Results

The status, experience, updates, attitude, interest of medical apprentices on animal trial research responses were (82% interested), 3R’s awareness in research, (34% Replace, Recur, Research), 42% accepted scientific research is carried out in animals as there are no other alternatives, also to find an alternative to animal use in research and the standards are not high enough in conducting the animal trials. 48% strongly agreed that ethical regulation is needed in animal research. 82% perceptions for developing new procedures and treatments, medical diagnosis, and advancements in animal research trials. 50% strongly agree that animal trials are enough to perform for processing human trials.

Conclusion

The study concluded that the majority of the medical students and clinicians interested in animal research trials, only a few participate in research during the medical training period.

Publication Facts

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Author statements

Data availability

N/A

16%

External funding

No

32%

Competing interests

N/A

11%

This journal

Other journals

Articles accepted

19%

33%

Days to publication

0

145

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Editor & editorial board: profiles
Academic society: N/A
Publisher: MM Publications

References

Von Roten FC. Public perceptions of animal experimentation across Europe. Public Underst Sci. 2013 Aug;22(6):691–703.

Ressler KJ, Mayberg HS. Targeting abnormal neural circuits in mood and anxiety disorders: from the laboratory to the clinic. Nat Neurosci. 2007 Sep;10(9):1116–24.

Worcester RM, Chairman M. Science and democracy: Public attitudes to science and scientists. In: World Conference on Science [Internet]. 1999.

Neilson EG. The role of medical school admissions committees in the decline of physician-scientists. J Clin Invest. 2003 Mar;111(6):765–7.

Khan H, Khawaja M. Impact of a workshop on the knowledge and attitudes of medical students regarding health research Journal of college of physicians and surgeons Pakistan 2007;17(1).

Nerlekar S, Karia S, Harshe D, Warkari R, Desousa A. Attitude and Knowledge of Undergraduate Medical Students towards the Use of Animals in Medical Research: An Exploratory Study. J Clin Diagn Res [Internet]. 2018;12(7).

Kimmel AJ. Ethical Issues in Behavioral Research: Basic and Applied Perspectives. John Wiley & Sons; 2009. 432 p.

Alghamdi KM, Moussa NA, Alessa DS, Alothimeen N, Al-Saud AS. Perceptions, attitudes and practices toward research among senior medical students. Saudi Pharm J. 2014 Apr;22(2):113–7.

Pinto A, De Santis M, Moretti C, Farina L, Ravarotto L. Medical practitioners’ attitudes towards animal assisted interventions. An Italian survey [Internet]. Vol. 33, Complementary Therapies in Medicine. 2017. p. 20–6.

Beversdorf DQ, Adams NR. Attitudes Toward Animal Research Among Medical Students in the United States. J Am Assoc Lab Anim Sci. 2020 Mar 1;59(2):120–6.

Siemens DR, Punnen S, Wong J, Kanji N. A survey on the attitudes towards research in medical school. BMC Med Educ. 2010 Jan 22;10:4.

Timothy CN, Samyuktha PS, Brundha MP. Dental pulp Stem Cells in Regenerative Medicine – A Literature Review [Internet]. Vol.12, Research Journal of Pharmacy and Technology. 2019. p. 4052.

Brundha MP,Pathmashri VP, Sundari S. Quantitative Changes of Red Blood cells in Cancer Patients under Palliative Radiotherapy-A Retrospective Study. Research Journal of Pharmacy and Technology; Raipur. 2019 Feb;12(2):687–92.

Gawda B, Czubak K. Prevalence of Personality Disorders in a General Population Among Men and Women [Internet]. Vol. 120, Psychological Reports. 2017. p. 503–19.

Vignesh P, Vijayashree PJ, Brundha MP. Novel Mutations Associated with Amelogenesis Imperfecta- A Review. Indian J Forensic Med Toxicol. 2020 Oct 29;14(4):4841–6.

Rajeswaran S, Brundha MP, As S. TafiIn Fibrinolysis-A Review. European Journal of Molecular & Clinical Medicine. 2020;7(1):2973–81.

Harsha L, Brundha MP. Role of collagen in wound healing. Drug Invention Today [Internet]. 2020;13(1).

Aparna J, Brundha MP. Matrix Metalloproteinases (MMPS) and its Role in Cancers-A Review. Indian J Forensic Med Toxicol [Internet]. 2020;14(4).

Vidyashri S, Somasundaram J, Brundha MP. PRION PROTEINS AND DIABETES MELLITUS - A REVIEW. European Journal of Molecular & Clinical Medicine. 2020 Nov 22;7(1):1520–8.

Wilms' tumor: An update. Indian J Urol. 2007;23:458-66.

Khanna G, Naranjo A, Hoffer F, Mullen E, Geller J, Gratias EJ et al. Detection of preoperative wilms tumor rupture with CT: a report from the Children's Oncology Group. Radiology. 2013;266:610-7.

Hennigar RA, O'Shea PA, Grattan-Smith JD. Clinicopathologic features of nephrogenic rests and nephroblastomatosis. Adv Anat Pathol. 2001;8:276-89.