Encapsulated Oncocytic Variant Of Papillary Thyroid Carcinoma With Extensive Infarction: A Diagnostic Dilemma Case Report
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Abstract
Oncocytic variant of Papillary Thyroid carcinoma (PTC) is a rare subtype of PTC. Diagnosis is based on the oncocytic tumor cells showing nuclear features of PTC in more than 75% of the tumor. We describe one such rare occurrence in a 45 year old male who was diagnosed as a hurtle cell neoplasm on Fine Needle Aspiration and underwent hemithyroidectomy. Gross specimen revealed near total infarction of tumor due to prior FNA. However careful and extensive sampling of the periphery of the tumor revealed oncocytic tumor cells with classic nuclear features of PTC showing positivity for CK7, CK19, CD56, TTF-1. There was no evidence of capsular or vascular invasion. Thus the case was diagnosed as encapsulated oncocytic variant of PTC. The pitfalls in diagnosis are discussed in detail.
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