INDICATORS OF BIOLOGICAL RESPONSES
Literature review
DOI:
https://doi.org/10.56501/intjprosthorehab.v2i1.213Keywords:
Host response; Ro and anti-inflammatory mediators; Bone resorption mediators; Biomarkers;Altered response.Abstract
Despite the fact that dental implants have predictable outcomes and are a common technique in everyday clinical practice for oral
rehabilitation, the formation and advancement of peri-implantitis has significantly harmed implant survival and success. Periimplantitis is a well-known inflammatory condition that causes soft tissue inflammation as well as progressive bone loss that goes
beyond biological osseous remodelling Importantly, earlier research has shown that the presence of periodontopathogens is
necessary but not sufficient for the onset of peri-implantitis, and that osteo-immunoinflammatory mediators released by the host
response have a significant impact on peri-implant tissue disintegration Given the lack of predictable and effective therapeutic
interventions for the treatment of peri-implantitis scientific evidence pertaining to the host response profile around dental implants
may be critical in the future for providing a wider preventive and/or therapeutic window for this peri-implant lesion, indicating
biomarkers that provide quantifiable measures of response to peri-implant therapy.
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