EFFECTIVENESS OF BROMELAIN MOUTHRINSE IN GINGIVAL INFLAMMATION AND BACTERIAL PLAQUE AMONG ADOLESCENTS: A RANDOMIZED CLINICAL TRIAL

Original article

Authors

  • Channesh Patel Senior Lecturer, Dept of Conservative and Endodontics, College of Dental Science, Davangere-577004
  • Sathya Kumaresan Post graduate, Dept of public health dentistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Poonamallee, Chennai-600077

DOI:

https://doi.org/10.56501/intjcommunitydent.v10i2.600

Keywords:

Bromelain, Sreptococcus mutans, herbal extracts, antioxidants

Abstract

Background: Mouthwashes are adjunct to regular brushing and flossing. Chlorhexidine is considered as a gold standard among mouth rinses. However, the most commonly known side effects include discolouration of teeth and the tongue particularly on the dorsum part. Hence the study was conducted to evaluate the effectiveness of Bromelain mouth rinse in gingival inflammation and bacterial plaque among adolescents.

Methods and methodology: This double-blinded, randomized controlled trial was conducted in accordance with Consolidated Standards of reporting Trials (CONSORT) in Public Health Dentistry Department at Saveetha University. The protocol was approved by the Institutional Review Board (IRB). 30 patients with moderate gingivitis were included in the study. All subjects signed an IRB-approved consent form. Participants from 15 to 19 years are recruited from the Urban health programmes through dental camps.

Results: No attempt was made for oral prophylaxis before the commencement of the study. The severity of gingivitis and plaque accumulation were assessed by gingival and plaque indices. Gingival index (Löe and Silness, 1963) and plaque index (Löe, 1967) were measured initially at baseline The trial was followed up for 30 days. The participants were instructed to rinse with plain water thoroughly. They were then directed to spit into a sterile plastic container after 5 minutes.At baseline, there was no significant difference in GI and PI scores among the groups (P=0.78 and 0.62) respectively. At one month follow up, there was significant difference in the mean GI and PI scores (P=0.02 and P=0.01) respectively.

Conclusion: Bromelain mouthwash is beneficial in improving gingival status due to its profound styptic action, with sufficient reduction in plaque scores without any adverse effects.

 

References

Manchanda K, De Sarkar A. Quality of Life: A Prerequisite to Action for Oral Health Care. LAP Lambert Academic Publishing; 2014. 68 p.

Taani DQ, El-Qaderi SS, Alhaija EA. Dental anxiety in children and its relationship to dental caries and gingival condition [Internet]. Vol. 3, International Journal of Dental Hygiene. 2005. p. 83–7. Available from: http://dx.doi.org/10.1111/j.1601-5037.2005.00127.x

Eick S. Oral Biofilms. Karger Medical and Scientific Publishers; 2020. 232 p.

Romeo T. Bacterial Biofilms. Springer Science & Business Media; 2008. 294 p.

Sultana S, Parvin R, Parvin MS, Islam MT, Bari ASM, Chowdhury EH. Prevalence of Methicillin and Lactamase Resistant Pathogens Associated with Oral and Periodontal Disease of Children in Mymensingh, Bangladesh. Pathogens [Internet]. 2022 Aug 9;11(8). Available from: http://dx.doi.org/10.3390/pathogens11080890

Tabesh M, Sh ME, Etemadi M, Naddaf F, Heidari F, Alizargar J. The antibacterial activity of nasturtium officinale extract on common oral pathogenic bacteria. Niger J Clin Pract. 2022 Sep;25(9):1466–75.

Borgström MK, Edwardsson S, Sullivan Å, Svensäter G. Dental plaque mass and acid production activity of the microbiota on teeth [Internet]. Vol. 108, European Journal of Oral Sciences. 2000. p. 412–7. Available from: http://dx.doi.org/10.1034/j.1600-0722.2000.108005412.x

Padol MV, Vishwakarma P, Dodamani AS, Gore AW, Chachlani KS, Kharkar SP. Comparative evaluation of nutmeg mouthwash and 0.2% chlorhexidine gluconate mouthwash on halitosis and plaque control: A randomized clinical trial. J Indian Soc Periodontol. 2022 Jul;26(4):384–9.

Comparison of Antibacterial Efficacy of Different Herbal Mouthwashes – An in Vitro Study. Indian Journal of Public Health Research & Development. 2020. Available from: http://dx.doi.org/10.37506/ijphrd.v11i6.9798

P. Kalyani, L. Leelavathi. Comparison between the effect of plain water, herbal mouthwash, and chlorhexidine mouthwash on salivary pH. Drug Invention Today, 2019, 11(5): 1184-1187

Pavan R, Jain S, Shraddha, Kumar A. Properties and therapeutic application of bromelain: a review. Biotechnol Res Int. 2012 Dec 10; 2012: 976203.

Bhadbhade SJ, Acharya AB, Rodrigues SV, Thakur SL. The antiplaque efficacy of pomegranate mouthrinse. Quintessence Int. 2011 Jan; 42(1):29–36.

López Villarreal SM, Elizondo Luévano JH, Pérez Hernández RA, Sánchez García E, Verde Star MJ, Castro Ríos R, et al. Preliminary Study of the Antimicrobial, Anticoagulant, Antioxidant, Cytotoxic, and Anti-Inflammatory Activity of Five Selected Plants with Therapeutic Application in Dentistry. Int J Environ Res Public Health. 2022 Jun 28;19(13). Available from: http://dx.doi.org/10.3390/ijerph19137927

Moghadam ET, Yazdanian M, Tahmasebi E, Tebyanian H, Ranjbar R, Yazdanian A, et al. Current herbal medicine as an alternative treatment in dentistry: In vitro, in vivo and clinical studies. Eur J Pharmacol. 2020 Dec 15; 889:173665.

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Published

2022-08-21

How to Cite

Channesh Patel, & Sathya Kumaresan. (2022). EFFECTIVENESS OF BROMELAIN MOUTHRINSE IN GINGIVAL INFLAMMATION AND BACTERIAL PLAQUE AMONG ADOLESCENTS: A RANDOMIZED CLINICAL TRIAL: Original article. International Journal of Community Dentistry, 10(2), 64–69. https://doi.org/10.56501/intjcommunitydent.v10i2.600