Oral Squamous Acanthoma – A Histopathologic Entity Or Not

Case Report

Authors

  • Snega Thamilselvan Senior Lecturer Department of Oral & Maxillofacial Pathology Chettinad Dental College & Research Institute Kelambakkam

DOI:

https://doi.org/10.56501/intjhistopatholinterpret.v13i1.1067

Keywords:

Acanthoma, benign, dysplasia, papilloma, trauma

Abstract

Oral squamous acanthoma (OSA) is an uncommon benign epithelial lesion of the oral cavity, presenting as a solitary, painless, sessile or pedunculated mass. It is considered a variant of oral squamous papilloma, characterized by acanthosis without papillomatosis. Although typically asymptomatic, OSA can cause discomfort or functional impairment depending on its size and location. Diagnosis is primarily based on clinical and histopathological examination, with characteristic features including hyperkeratosis, acanthosis, and elongated rete ridges. Treatment involves conservative surgical excision, with a low recurrence rate reported in the literature. Here, we present a rare case of OSA in a 55-year-old female patient, highlighting its clinical and histopathological characteristics, differential diagnosis, and management. This case underscores the importance of considering OSA in the differential diagnosis of oral lesions and the significance of histopathological analysis in confirming the diagnosis.

References

Groeger, S., & Meyle, J. (2019). Oral Mucosal Epithelial Cells. Frontiers in immunology, 10, 208. https://doi.org/10.3389/fimmu.2019.00208

Tomich, C. E., & Shafer, W. G. (1974). Squamous acanthoma of the oral mucosa. Oral Surgery, Oral Medicine, Oral Pathology, 38(5), 755–759. doi:10.1016/0030-4220(74)90396.

Prokopios, P., Argyris., Zachary, M., Slama., Andrew, C., Nelson., Ioannis, G., Koutlas. (2019). Solitary oral epidermolytic acanthoma: Case report of a rarely diagnosed entity.. Oral Surgery, Oral Medicine, Oral Pathology, and Oral Radiology, doi: 10.1016/J.OOOO.2019.03.016

Abbey, L. M., Sawyer, D. R., & Syrop, H. M. (1978). Oral squamous acanthoma. Oral Surgery, Oral Medicine, Oral Pathology, 45(2), 255–260. doi:10.1016/0030-4220(78)90092

Tran TAN, Parra O, Linos K. Hyaline Inclusion Acanthoma. Am J Dermatopathol. 2021 Jul 1;43(7):525-529. doi: 10.1097/DAD.0000000000001927. PMID: 33606370.

Jakobiec FA, Mendoza PR, Colby KA. Clinicopathologic and immunohistochemical studies of conjunctival large cell acanthoma, epidermoid dysplasia, and squamous papilloma. Am J Ophthalmol. 2013 Oct;156(4):830-46. doi: 10.1016/j.ajo.2013.05.005. Epub 2013 Jun 17. PMID: 23786782.

Tavasoly A, Gholami H, Rostami A et al. Clinico-histopathologic and outcome features of cutaneous infundibular keratinizing acanthoma: a case report and literature review. World J Surg Oncol. 2014 Jun 3;12:173. doi: 10.1186/1477-7819-12-173. Retraction in: World J Surg Oncol. 2016 Nov 4;14 (1):282. PMID: 24890648; PMCID: PMC4050395.

Pătraşcu V, Geoloaica L, Ciurea RN. Clear Cell Acanthoma with Atypical Location -Case Report and Literature Review. Curr Health Sci J. 2018 Oct-Dec;44(4):397-400. doi: 10.12865/CHSJ.44.04.13. Epub 2018 Dec 31. PMID: 31123619; PMCID: PMC6421483.

S., Sivaharini., Herald, J, Sherlin., Vivek, Narayan. (2020). Reactive lesions of the oral cavity - A retrospective study. International Journal of Research in Pharmaceutical Sciences, doi: 10.26452/IJRPS.V11ISPL4.4076

Justyna, Farynowska., Katarzyna, Błochowiak., Dorota, Trzybulska., Marzena, Wyganowska-Świątkowska. (2018). Retrospective analysis of reactive hyperplastic lesions in the oral cavity. Journal of Clinical and Experimental Medicine, doi: 10.15584/EJCEM.2018.2.2

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Published

2024-05-22

How to Cite

Thamilselvan, S. (2024). Oral Squamous Acanthoma – A Histopathologic Entity Or Not: Case Report. International Journal of Histopathological Interpretation, 13(1), 17–21. https://doi.org/10.56501/intjhistopatholinterpret.v13i1.1067