Rare Spindle Cell Lesion Of Parotid Gland: Solving The Dilemma
Case Report
DOI:
https://doi.org/10.56501/intjhistopatholinterpret.v12i2.889Keywords:
Dermatofibrosarcoma, staghorn vessels, storiform pattern, spindle cells, CD34Abstract
Dermatofibrosarcoma of parotid gland is rare. Microscopic examination showed spindle cells arranged in storiform pattern, having monomorphic ovoid nuclei, moderate to abundant eosinophilic cytoplasm with staghorn-shaped blood vessels. Differential diagnosis of solitary fibrous tumour, DFSP, schwannoma, synovial sarcoma were kept and finally Immunohistochemistry solved the dilemma as Vimentin, CD34, STAT-6 & S-100 were applied. Tumor showed Vimentin & CD 34 positivity, while STAT-6 & S-100 were negative.
References
Hegde U, Shetty SK, Sreeshyla HS, Doddawada VG. Dermatofibrosarcoma protuberans - a recurrent lesion with unusual presentation in the parotid region. J Clin Diagn Res. 2014 ;8(3):130-131.
Bague S, Folpe AL. Dermatofibrosarcoma protuberans presenting as a subcutaneous mass: a clinicopathological study of 15 cases with exclusive or near-exclusive subcutaneous involvement. Am J Dermatopathol. 2008 ;30(4):327-332.
Adilbay D, Khozhamkul F, Toiynbekova S, Ahmetov D. A case of aggressive giant dermatofibrosarcoma protuberance occurring in the parotid gland. Int J Surg Case Rep. 2019;55:58-61.
Ghaloo SK, Dhanani R, Pasha HA, Awan MS, Memon A. Recurrent Dermatofibrosarcoma Protuberans of the Parotid: A case report and review of literature. J Pak Med Assoc. 2019;69(1):113-115.
D Lemm, LO Mugge, T Mentzel, K Hoffken. Current treatment options in dermatofibrosarcoma protuberans. J Cancer Res Clin Oncol. 2009;135(5):653–665.
Lee OJ ,Pi DY, Jo DH ,Kim KJ ,Ro JY. Dermatofibrosarcoma protuberance of the parotid gland: A case report. The Korean J of Pathol. 2004; 38: 276-279.
Li N, Zhou T, Chen S, Yang R, Zhu Q, Feng Z. COL1A1-PDGFB gene fusion in dermatofibrosarcoma protuberans: a useful diagnostic tool and clinicopathological analysis. Int J Clin Exp Pathol. 2018 Aug 1;11(8):4052-4059.
Bramati C, Melegatti MN, Lalla F, Giordano L. Management of two rare cases of dermatofibrosarcoma protuberans arising in the parotid region. BMJ Case Rep. 2021 Jun 17;14(6)
Ilson S, Alex U, JoaquínU, Pablo M, Pamela V, Cesar G. Dermatofibrosarcoma Protuberans of The Face: A Case Report And Review of The Literature. Canc Therapy & Oncol Int J. 2017; 3(2): 5.
Khalid S, Dhanani R, Pasha H. A, Awan M, Memon A. Recurrent Dermatofibrosarcoma Protuberans of the Parotid: A case report and review of literature. Journal of Pakistan Medical Association 2019;69(1):113-115
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Copyright (c) 2023 Bushra Siddiqui, Veena Maheshwari, Medha Mani Gupta, Sadaf Abbas
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