Chlorhexidine and the Degradation of the Hybrid Layer – Narrative Review
Chlorhexidine and the Degradation of the Hybrid Layer
DOI:
https://doi.org/10.56501/intjorofacres.v8i1.1043Keywords:
Hybrid layer, Chlorhexidine, Degradation, Metalloproteinases, Adhesive resin layerAbstract
Introduction: The clinical lifespan of restoration is based on resistance that the hybrid layer structure performs to degradation that is influenced by several local factors, with short-term or long-term action effects on the tooth.
Method: The purpose of this study includes the presentation of published data about advantages and disadvantages that the use of one of the most advertised dentinal solutions, such as chlorhexidine brings to resistance of hybrid layers to structural degradation. The way the adhesive resin is connected to acidified dentinal structure depends on physical or chemical factors of this connection between two structures with very different characteristics. The study is of review type, using key words and their combination in PubMed electronic search pages.
Results: Chlorhexidine is known for its inhibitory properties against activated dentinal metalloproteinases, a consequence of acidification process, stage of the protocol for the realization of dentinal restorations realized with composite. Thus, this surface area is directly proportional to its size versus the duration of clinical use of dental composite restoration. Microretention is realized between acidified dentin or enamel and extensions of adhesive resin against pre-prepared spaces, dentinal tubules.
Short conclusion: During acidification process, the precursor to placement of adhesive resin layer, metalloproteinases of dental origin are also activated, enzymes which are responsible for degradation of hybrid layer. These enzymes have their expressed activity depending on the presence of Zn2+ or Ca2+ ions. There are several ways of inhibiting these enzymes, and there are several ways of inhibiting degradation process of hybrid layer.
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