Omics’ in oral cancer: A comprehensive review

Authors

  • Sanpreet Singh Sachdev Government Dental College and Hospital, Mumbai https://orcid.org/0000-0001-7655-8180
  • Manisha Ahire Sardar Government Dental College and Hospital, Mumbai
  • Jagdish Tupkari Government Dental College and Hospital, Mumbai
  • Tabita Joy Chettiankandy Government Dental College and Hospital, Mumbai
  • Shubhangi Dalvi Grant Government Medical College and Hospital, Mumbai
  • Zaneta D'Souza Government Dental College and Hospital, Mumbai

DOI:

https://doi.org/10.56501/intjorofacres.v6i2.152

Keywords:

Genomics, Transcriptomics, Proteomics, Metabolomics, Salivaomics

Abstract

Health and disease states are dictated or accompanied by corresponding alterations in genes, mRNAs, proteins and metabolites. Over the past few decades, various ‘omic’ technologies have been developed to study the genome, transcriptome, proteome and metabolome respectively. Since oral cancers are one of the leading causes of death globally, much of research work has attempted to study the analytes in cancerous conditions by utilizing the various ‘omic’ modalities. These studies have aimed to understand the pathogenesis of head and neck cancers, aid in their diagnosis, devise new treatment strategies, and improve prognosis. It is imperative for surgeons and pathologists to be in line with the updates pertaining to various ‘omic’ methodologies available for studying the analytes. The present review comprehensively describes the development of various ‘omic’ technologies, including- genomics, transcriptomics, proteomics and metabolomics, while emphasizing their applicability in oral cancers.

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Published

08-11-2022

How to Cite

1.
Sachdev SS, Sardar MA, Tupkari J, Chettiankandy TJ, Dalvi S, D'Souza Z. Omics’ in oral cancer: A comprehensive review. Int J Orofac Res [Internet]. 2022 Nov. 8 [cited 2025 Jan. 1];6(2):28-3. Available from: https://editorialmanager.in/index.php/ijofr/article/view/152

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